In 20 century, positive philosophy and experimental science are developed to be system science and synthetic philosophy. System bioscience is founded by Von.Bertalanffy at the aspects of theory biology and general system theory.
Biosystem science or system bioscience, is investigated in the fields of structure, pattern of biosystems at the levels of molecule, cell, organ and population, especially the psychological and genetic information system.
The system biological engineering, is exploring of engineering technology of biosystems by both experimental analysis and system logic methodology, included the aspects of ecological, genetic, bionic and intelligence engineering, which will promote the development of system medicine, transgenic bioreactor, bio-computer, intelligence robots and modernism of TCMedicine edtc.
In 1970s, Paul. D .Boyer and Walter Kohn discovery techniques of DNA recombination. In 1980s, there are inventions of concepts of artificial intelligence and bio-molecular chips. Therefore, the time of system biological engineering is coming in the near future.
System Biological Engineering, included: 1). Cell fertilization, microbial fermentation, industrial ecology etc. biochemical and ecological engineering; 2).Cell hybridization, gene recombination, transgenic bioreactor etc. embryo and genetic engineering; 3). Biosensor, enzyme, organelles, molecular element, DNA nanotechnology etc. biomedical and bionic engineering; 4). Genetic computation, artificial nerve network etc. bio-computation and intelligence engineering, etc. From the revolution of industry in England till the modernism industrial network, engineering of ecological city, industrial chain and products cycle is very important for the human being to live harmony with the nature.
1. Ben J. Zeng, On the concept of system biological engineering, Communication on Transgenic Animals, No. 6, June, 1994.
2. Ben J. Zeng, Transgenic avian used as oviduct bioreactorInternational Exhibition and Symposium on Biotechnology and Pharmaceutical Industries, Shanghai, China, July 15-20, 1995.